K+2 Potassium™ is a uniquely formulated potassium product composed of potassium bicarbonate and potassium bound to the amino acid glycine, which gives this product optimal potency, stability and tolerability. Potassium is the third most abundant mineral in the body after calcium and phosphorus. Total body potassium content is about 30-40 grams, 98% of which is contained inside cells, mostly in skeletal muscle. Potassium is the most abundant positively charged intracellular electrolyte. Potassium concentrations are about 30 times higher inside cells than outside, compared to the concentration of sodium, which is 10 times lower inside cells than outside. This difference is what creates the membrane potential, an electrochemical gradient across the cell membrane essential for proper muscle contraction, nerve impulse transmission, hormone secretion from endocrine glands, and cardiac muscle function. As much as 20%-40% of an adult’s resting energy expenditure is dedicated to maintaining this critical electrochemical balance, via sodium-potassium-ATPase pumps. Potassium is abundant in vegetables, fruits, beans and nuts, with smaller amounts in animal foods. Owing to this relative ubiquity, overt potassium deficiency is rare, but suboptimal intake may lead to signs and symptoms of insuffciency, which may include fatigue, lethargy, muscle weakness, cramping or twitching, heavy legs, constipation, intestinal paralysis (resulting in delayed gastric emptying, bloating and abdominal pain), and cardiac arrhythmias.1,2 Inadequate dietary intake does not typically result in hypokalemia (dangerously low blood potassium), but the risk factors for potassium deficiency in the sidebar should be noted.
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